Nonfunctioning Allografts Play an Important Role in Parathyroid Hormone and Calcitonin Metabolism

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Nonfunctioning allografts play an important role in parathyroid hormone and calcitonin metabolism.

Dr. Mehmet Şükrü Sever Ataköy, 4. Kisim, TO Blok No: 216, D:15 Bakirköy İstanbul (Turkey) Dear Sir, The kidneys (together with the liver) are responsible for most of the metabolism of polypeptide hormones; furthermore some hormones such as calcitonin (CT) and the N-terminal fragment of parathyroid hormone (PTH) are not metabolized by the liver, hence the role of the kidneys becomes more importa...

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In mammals, phosphocalcic and bone metabolisms are mainly regulated by parathyroid hormone, parathyroid hormone-related peptide (PTHrP) and 1α,25-dihydroxyvitamin D or calcitriol. In camels, circulating levels of calcitriol are 10 times higher than those determined in other ruminants and further increase during early lactation. Calcitriol and parathyroid-related peptide stimulate intestinal abs...

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Parathyroid Hormone and Mitochondrial Metabolism

The effects of parathyroid hormone upon substrate decarboxylation and ion uptake and release in isolated mitochondria in terms of specificity, sensitivity, and the correlation between action in vivo and in vitro were studied, Parathyroid hormone added to isolated liver or kidney mitochondria in vitro stimulated the decarboxylation of a variety of Krebs’ cycle intermediates. This decarboxylation...

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Serum parathyroid hormone and calcitonin levels in racehorses with fracture.

Serum parathyroid hormone (PTH) and calcitonin (CT) levels in fractured racehorses were measured by radioimmunoassay. Racehorses with fracture of large bone such as the radius, third metacarpus, third carpus, digital bone or tibia, showed normal PTH level and elevated CT level in the serum. Serum PTH level was slightly higher in racehorses with sesamoid bone fracture compared to that of healthy...

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The principal hormones involved in calcium metabolism and bone remodeling are parathyroid hormone (PTH), calcitonin, and vitamin D (D3). Other hormones, such as the thyroid hormones, growth hormone, androgens, estrogens, and the glucocorticoids also influence mineral homeostasis and bone metabolism. The three primary target tissues for these hormones are bone, kidney, and intestine. These three...

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ژورنال

عنوان ژورنال: Nephron

سال: 1990

ISSN: 1660-8151,2235-3186

DOI: 10.1159/000186202